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MALT lymphoma
4 associated genes
42 connected diseases
16 signs/symptoms
Disease Type of connection
Precursor B-cell acute lymphoblastic leukemia
Follicular lymphoma
Intellectual disability-severe speech delay-mild dysmorphism syndrome
Mantle cell lymphoma
Hypohidrotic ectodermal dysplasia with immunodeficiency
Autosomal dominant hypohidrotic ectodermal dysplasia
Anhidrotic ectodermal dysplasia - immunodeficiency - osteopetrosis - lymphedema
Incontinentia pigmenti
X-linked mendelian susceptibility to mycobacterial diseases due to IKBKG deficiency
Autosomal dominant nonsyndromic sensorineural deafness type DFNA
Giant cell glioblastoma
Gliosarcoma
Young adult-onset Parkinsonism
Herpetic encephalitis
Intermittent hydrarthrosis
TRAPS syndrome
Persistent polyclonal B-cell lymphocytosis
Severe combined immunodeficiency due to CARD11 deficiency
7q31 microdeletion syndrome
Childhood apraxia of speech
Amyotrophic lateral sclerosis
Bartsocas-Papas syndrome
LEOPARD syndrome
Noonan syndrome
Pilocytic astrocytoma
X-linked lymphoproliferative disease
Autoinflammatory syndrome with pyogenic bacterial infection and amylopectinosis
Burkitt lymphoma
Precursor T-cell acute lymphoblastic leukemia
X-linked distal arthrogryposis multiplex congenita
Autoimmune lymphoproliferative syndrome with recurrent infections
Autosomal recessive limb-girdle muscular dystrophy type 2H
Bardet-Biedl syndrome
Behçet disease
Blau syndrome
Cerebellar ataxia - hypogonadism
Chronic mucocutaneous candidiasis
Chuvash erythrocytosis
Severe intellectual disability-poor language-strabismus-grimacing face-long fingers syndrome
Von Hippel-Lindau disease
X-linked hyper-IgM syndrome
Hyper-IgM syndrome type 3
Synonym(s):
- Extranodal marginal zone B-cell lymphoma
- MALToma
- Mucosa-associated lymphatic tissue lymphoma
- Mucosa-associated lymphoid tissue lymphoma
Classification (Orphanet):
- Rare hematologic disease
- Rare oncologic disease
Classification (ICD10):
- Neoplasms -
Epidemiological data:
Class of prevalence: 1-9 / 100 000
Average age onset: adulthood
Average age of death: normal
Type of inheritance: multigenic/multifactorial
External references:
No OMIM references
No MeSH references
Gene symbol UniProt reference OMIM reference
BIRC3 Q13489601721
FOXP1 Q9H334605515
IGH Q6P089
MALT1 Q9UDY8604860
Very frequent
- Asthenia / fatigue / weakness
- Epigastralgia / heartburn / gastric / duodenal ulcer / gastritis
- Fever / chilling
- Hematologic / blood / lymphatic cancer
- Hyperhidrosis / increased sweating
- Lung / pulmonary infiltrates
- Nausea / vomiting / regurgitation / merycism / hyperemesis
- Weight loss / loss of appetite / break in weight curve / general health alteration

Frequent
- Constipation

Occasional
- Acute abdominal pain / colic
- Chronic uveitis / blepharitis / episcleritis / scleritis / conjonctivitis / keratitis
- Defect / anomaly of lacrimal system
- Lymphadenopathy / polyadenopathies
- Mediastinal / hilar adenopathies
- Repeat respiratory infections
- Thyroid anomalies